What are Anabolic Steroids?

What are Anabolic Steroids?

What are Anabolic Steroids?

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ANABOLIC STEROIDS are synthetic (artificial) analogues of the male sex hormone TESTOSTERONE.

What is hidden under this terrible definition of “Anabolic Steroids”? Generally speaking, male sex hormones. Substances that are very natural to the male body. They cause the development of secondary sexual characteristics in men, are responsible for sexuality, contribute to the growth of muscle tissue by increasing protein synthesis in muscles. The latter is called anabolism and that is why drugs that lead to such growth are often called anabolic steroids.

Anabolic steroids synthesisThe sex hormone moleculeAnabolic and androgenic index
Anabolic steroids were synthesized after the war, although positive experiments on the transplantation of gonads were carried out at the beginning of the last century, which led to the rejuvenation and improvement of well-being in subjects.
The sex hormone molecule was slightly modified in the laboratory in order to enhance the anabolic properties (what accelerates protein synthesis) and to decrease androgenic properties (from which secondary sex characteristics develop), and as a result anabolic steroids appeared from androgenic steroids.
Although, basically, in addition to the anabolic index, any anabolic steroid also carries androgenic one.

TESTOSTERONE performs many of the most important functions in the body and one of the most important is the formation of male signs, including the growth of muscle mass! The hormone travels in the blood throughout the body and can affect its activity (in our case, it can accelerate the synthesis of new proteins in the muscle cell).

Male testosterone production with age
Male testosterone production with age

Testosterone is synthesized from cholesterol (cholesterol-androstenedione-testosterone) in the TESTES.

  • for MEN = 6-7 milligrams per day
  • for WOMEN = 1 milligram per day

In general, there are a lot of different hormones in our body:

  1. PEPTIDE HORMONES: (amino acid chains) insulin, growth hormone
  2. AMINO ACID DERIVATIVES: adrenaline, tyrosine
  3. STEROID HORMONES: testosterone, estrogen, cortisol, progestins

But now we are considering steroid hormones. Or rather, artificial testosterone analogues, which are called ANABOLIC STEROIDS.

There are many of them, because scientists have made different modifications of the original hormone molecule. Some modifications can aromatize (turn into female sex hormones), while some cannot. Some form a more stable bond with the receptor, some less stable. In general, different steroids have slightly different features. But in general, they all enhance protein synthesis in the cell, because they are similar to natural testosterone.

The next one: Types of Anabolic Steroids

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