Previous post: PCT (post cycle therapy)
I have already talked a lot about human growth hormone, despite the fact that very few athletes can afford this elite drug. However, since we decided to collect all the basic practical information about anabolic steroids in one place, then I have to repeat HERE what I have already said about this dope.
Why is growth hormone considered an “ELITE” drug? There are a lot of different reasons for this. But there are two main ones:
- High efficacy.
- Difficult production.
The difficult production and the high demand for growth hormone are the reason for its HIGH VALUE.
Miracles of Growth Hormone
But people would never spend such big money on growth hormone cycles if it didn’t work. Growth Hormone doesn’t just work. It is able to do what no other drug can do. What are these miracles? I will cite only THREE:
As you can see, the “pluses” of growth hormone are very significant. That is why, despite the fact that the IOC banned Hormone Growth in 1989, its use is not reduced. On the contrary, it is increasing all over the world, among both athletes and ordinary people. There’s no law against living the good life… in general…
GROWTH HORMONE – general information
GROWTH HORMONE (somatotropin) is one of the peptide hormones in the anterior lobe of the human pituitary gland that received this name because of its ability to cause bone growth in length in young people. Growth Hormone has a powerful ANABOLIC effect on MUSCLE GROWTH + a powerful CATABOLIC effect on FAT DESTRUCTION. The first is due to increased protein synthesis in two ways (about this later), and the second is due to the effect on lipolysis and carbohydrate metabolism in the body.
Now about carbohydrate metabolism. The fact is that HGH causes an increase in blood glucose levels. In this regard, the GROWTH HORMONE IS AN ANTAGONIST OF INSULIN! Therefore, it has a very strong effect on the pancreas, forcing it to produce more insulin than that’s provided by nature. Why? HGH – INSULIN are antagonists! Look carefully at this note:
- The Lower The Blood Sugar – the more HGH is produced.
- The Higher The Blood Sugar – the more Insulin is produced.
i.e. when HGH increases the level of glucose (sugar) in the blood, it causes more insulin to be made for BALANCE! When production is natural, it does not matter much. Imagine if you increase the concentration of HGH tenfold… and over the cycle of many months… In order to BALANCE “this whole holiday”, your pancreas will have to work hard by depleting its reserves. What can be provoked with TOO GREAT a burden for TOO LONG a time? A BREAKDOWN! The pancreas will simply not cope with the production of such a large amount of insulin needed for balance and will fail. This is called Diabetes Mellitus, baby! And that is why most well-informed people with long and large doses of HGH necessarily “help” their pancreas – with additional insulin injections. If you inject 4 IU per day for 2 weeks, then this is not critical. BUT if you inject 10-20 IU per day for 3-4 months… THIS IS MANDATORY! Usually 5 IU of short insulin a couple of times a day before large meals is enough.
In addition, without an adequate level of insulin, the anabolic effect of SOMATOTROPIN is not manifested. These two hormones are antagonists of each other in the situation when it comes to the CARBOHYDRATE EXCHANGE. If we are talking about the protein metabolism necessary for muscle growth, then insulin and growth hormone work synergistically! That is why children with diabetes do not grow well and are lagging behind in physical development from their peers. But we will talk about these combinations a bit later.
Now about the SYNTHESIS OF PROTEIN. As I told you, Growth Hormone has TWO main WAYS for this:
- DIRECT IMPACT on muscle cells through HGH receptors.
- EXPOSURE through the INTERMEDIARY – IGF-1 (IGF-1, Somatomedin C, Insulin-like Growth Factor)
Back in the 1970s, a whole group of “intermediaries” between HGH and target cells was identified. Then this group was called “somatomedins”. However, by the end of the 1980s, it became clear that there was only one “worker” — IGF-1 (all the other were “dummies”). IGF-1 is produced in the LIVER and in the MUSCULAR CELLS under the influence of HGH. IGF-1 has a pronounced anabolic effect on the target tissue. Especially on the muscles, bones, cartilage, skin, nerves, liver and kidneys. Thanks to IGF-1, there is a large increase in strength and local muscle growth. But IGF-1 cannot break down fats. In this regard, HGH and IGF-1 are not the same thing.